Potassium Citrate Supplier

Potassium Citrate

Description

Potassium Citrate serves as a pharmaceutical adjunct within veterinary medicine. Additionally, it finds application in various pharmacopeias and formulations such as potassium hydroxide solution, Cresol solution, and Soap solution. Furthermore, it functions as a buffering agent in beverages like fruit juices and colas such as R-cola.

Applications and Effects

Potassium Citrate primarily finds application in the Pharmaceutical Industry for formulating solutions that contribute to parenteral nutrition, the liquid utilized in preparing injections.

Potassium Citrate - Matrix Impex Your Global Supplier

Specifications

USP

Tests

Specifications

Description :

Transparent crystals or white granular powder; odorless saline taste, and is deliquescent when exposed to moist air.

Solubility :

Freely soluble in water. Almost insoluble in alcohol.

Identification :

A) A solution (1 in 20) responds to the test for Potassium and for citrate.
Potassium: A White crystalline precipitate that is soluble in 6N ammonium hydroxide.
Citrate: A light red color is produced.

Alkalinity :

No pink color is produced by 1 drop of phenolphthalein TS.

Loss on drying :

Between 3.0% and 6.0%. Dry it at 180°C for 4 hours.

Tartrate :

No precipitate is formed.

Heavy Metals :

Not more than 0.001%.

Assay :

99.0 % to 100.5 % (On dried basis)

Tests

Specifications

Appearance :

White or almost white, granular powder or transparent crystals, hygroscopic.

Solubility :

Very soluble in water, practically insoluble in ethanol (96%).

Identification
A. Citrates :

1. Violet colour, turning to violet-blue is produced.
2. A white precipitate is produced which is soluble in 6M acetic acid.

Identification
B. Potassium :

1. A yellow or orange-yellow precipitate is produced immediately.

Appearance of Solution :

Solution S is clear and colourless.

Acidity or Alkalinity :

Not more than 0.2 ml of 0.1M hydrochloric acid or 0.1M
Sodium Hydroxide is required to change the colour of the solution.

Readily Carbonisable Substances :

The solution is not more intensely coloured than reference
solution Y2 or GY2.

Chloride :

Not more than 50 ppm

Oxalate :

Not more than 300 ppm (calculated as anhydrous oxalic acid).

Sulphate :

Not more than 150 ppm

Heavy Metals :

Not more than 10 ppm

Sodium :

Not more than 0. 3 %

Water :

4.0 to 7.0 per cent, determined on 0.250 g.

Assay :

99.0 % to 101.0 % (On Anhydrous Basis)

Tests

Specifications

Description :

White granular crystals or a white crystalline powder; odourless; hygroscopic.

Solubility :

Very soluble in water; soluble in glycerin; practically insoluble
in ethanol (95%).

Identification
A. Potassium Salts :

1. A yellow or orange-yellow precipitate is produced.
2. A white crystalline precipitate is produced.
3. A yellow crystalline precipitate is produced, which on Ignition leaves a residue of KCL and platinum.

Identification
B. Citrates :

1. A white precipitate soluble in 6M acetic acid is produced.
2. A violet colour which turns violet-blue is produced.

Appearance of Solution :

Solution A is clear and colourless.

Acidity or Alkalinity :

Not more than 0.2 ml of 0.1M hydrochloric acid or 0.1M
sodium Hydroxide is required to change the colour of the solution.

Arsenic :

Not more than 2 ppm

Heavy Metals :

Not more than 10 ppm

Sodium :

Not more than 0.3 %

Chloride :

Not more than 100 ppm

Oxalate :

Not more than 300 ppm (calculated as anhydrous oxalic acid).

Sulphate :

Not more than 150 ppm

Readily Carbonisable Substances :

The solution is not more intensely coloured than reference
solution YS2 or GYS2

Water :

4.0 to 7.0 per cent, determined on 0.5 g.

Assay :

99.0 % to 101.0 % (On Anhydrous Basis)